Exploring the Role of Estrogen in Women's Cognitive Health During Aging

First Published: 01/08/2024

In a study published by Esperanza Navarro-Pardo, Carol A. Holland, and Antonio Cano in 2018, researchers reviewed the impact of declining estrogen levels on cognitive functions and psychological health in aging women. Estrogens, known for their role in reproduction, also significantly influence the central nervous system. This review focused on understanding how menopausal changes in estrogen levels affect cognition, mood, and overall psychological aging. The study highlighted the potential benefits of hormone therapy in mitigating cognitive decline, although findings remain inconclusive.

Key Findings:

1. Impact on Cognitive Function: Estrogen receptors are abundant in brain areas related to memory and cognition, suggesting a protective role of estrogens against cognitive decline.

2. Hormonal Therapy: While hormone therapy is proposed to balance cognitive functions during menopause, its efficacy and safety are still debated.

3. Psychological Health: The decline in estrogen levels is associated with increased risks of mood disorders, including depression and anxiety.

The study emphasises the need for further research to clarify the benefits and risks of hormone therapy and to understand the broader implications of estrogen decline on women's health.

References:

- Navarro-Pardo, E., Holland, C. A., & Cano, A. (2018). Sex Hormones and Healthy Psychological Aging in Women.

For more detailed information, you can read the full study here